ABSTRACT The Dimensional Change Card Sort (DCCS) is a measure of cognitive flexibility for children, which requires rule-use and shifting. Demographic, cognitive, regional cortical thickness, and genetic variables, including those related to language and executive function, were used to build predictive models of DCCS scores in 556 healthy pediatric participants. Gender, age, frontal, and temporal lobe regions of interest, and measures of sustained attention, inhibition, and word reading were selected as the best predictors of DCCS performance. Results indicated that DCCS performance is related to a broad range of cognitive functions and anatomic regions associated with various levels of cognitive function.

中文翻译：

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健康儿童和青少年执行功能的认知、神经解剖学和遗传预测因子

摘要 维度变化卡片分类 (DCCS) 是衡量儿童认知灵活性的指标，需要规则使用和转换。人口统计学、认知、区域皮质厚度和遗传变量，包括与语言和执行功能相关的变量，被用于构建 556 名健康儿科参与者的 DCCS 评分预测模型。性别、年龄、额叶和颞叶感兴趣区域以及持续注意力、抑制和单词阅读的测量被选为 DCCS 性能的最佳预测指标。结果表明，DCCS 的表现与广泛的认知功能和与各种认知功能水平相关的解剖区域有关。