ObjectivesSodium bromate is a strong oxidant, and bromate intoxication can cause irreversible severe-to-profound sensorineural hearing loss. This paper reports the first case in the English literature of bromate-induced hearing loss with hearing recovery measured by formal audiological assessment.Case reportA 72-year-old woman was admitted to hospital with complaints of profound hearing loss, nausea, diarrhoea and anuria after bromate ingestion in a suicide attempt. On admission, pure tone audiometry and auditory brainstem responses showed profound bilateral deafness. Under the diagnosis of bromate-induced acute renal failure and sensorineural hearing loss, continuous haemodiafiltration was performed. When dialysis was discontinued, pure tone audiometry and auditory brainstem responses showed partial threshold recovery from profound deafness.ConclusionSevere-to-profound sensorineural hearing loss is a common symptom of bromate intoxication. Bromate-induced hearing loss may be partially treated, and early application of continuous haemodiafiltration might be useful as a treatment for this intractable condition.

中文翻译：

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溴酸盐中毒导致耳聋的听力恢复

目的溴酸钠是一种强氧化剂，溴酸盐中毒可导致不可逆的重度至重度感音神经性听力损失。本文报道了英国文献中首例溴酸盐引起的听力损失并通过正式听力学评估测量听力恢复的病例。病例报告一名72岁的妇女因严重听力损失、恶心、腹泻和无尿入院。自杀未遂时摄入溴酸盐。入院时，纯音测听和听觉脑干反应显示严重的双侧耳聋。在诊断为溴酸盐引起的急性肾功能衰竭和感音神经性听力损失后，进行了持续性血液透析滤过。停止透析后，纯音测听和听性脑干反应显示重度耳聋部分阈值恢复。结论重度至重度感音神经性听力损失是溴酸盐中毒的常见症状。溴酸盐引起的听力损失可以得到部分治疗，早期应用连续血液透析滤过可能有助于治疗这种顽固性疾病。