In order to carry out their physiological functions, ion transport proteins must be targeted to the appropriate domains of cell membranes. Regulation of ion transport activity frequently involves the tightly controlled delivery of intracellular populations of transport proteins to the plasma membrane or the endocytic retrieval of transport proteins from the cell surface. Transport proteins carry signals embedded within their structures that specify their subcellular distributions and endow them with the capacity to participate in regulated membrane trafficking processes. Recently, a great deal has been learned about the biochemical nature of these signals, as well as about the cellular machinery that interprets them and acts upon their messages.

中文翻译：

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在极化细胞中转运蛋白运输。

为了执行其生理功能，必须将离子转运蛋白靶向细胞膜的适当结构域。离子转运活性的调节常常涉及严格控制细胞内转运蛋白向质膜的递送或从细胞表面内吞转运蛋白。转运蛋白携带嵌入其结构内的信号，这些信号指定其亚细胞分布并赋予其参与调节的膜运输过程的能力。近来，已经对这些信号的生化性质以及解释它们并根据其信息起作用的细胞机械学到了很多知识。