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Developmental genomic approaches in model organisms.
Annual Review of Genomics and Human Genetics ( IF 8.7 ) Pub Date : 2002-07-27 , DOI: 10.1146/annurev.genom.3.031302.100922
Valerie Reinke 1 , Kevin P White
Affiliation  

Functional genomics technologies can help decipher how information encoded in the genome is translated into morphology, physiology, and behavior during the development of complex organisms. A number of researchers have begun to apply DNA microarrays and other functional genomics approaches to study development. Here we review recent studies that take the first steps toward relating genome-wide information to developmental events, we discuss recent genomics approaches taken in animal model systems used to study human disease, and we outline methods that may be useful for constructing genome-wide maps of developmental processes.

中文翻译:

模型生物中的发育基因组学方法。

功能基因组学技术可以帮助解释在复杂生物体发育过程中,基因组中编码的信息如何转化为形态,生理学和行为。许多研究人员已开始将DNA微阵列和其他功能基因组学方法应用于研究发展。在这里,我们回顾了为将全基因组信息与发育事件相关联而采取的第一步的最新研究,我们讨论了用于研究人类疾病的动物模型系统中采用的最新基因组学方法,并概述了可能对构建全基因组图谱有用的方法发展过程。
更新日期:2019-11-01
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