The ability to link dietary consumption of prebiotic food ingredients and probiotic microorganisms to health benefits rests, in part, on our ability to identify both the extent to which these factors alter human microbiome activity and/or structure and the ability to engage eukaryotic cells necessary to transduce signals originating from the microbiome. The human microbiome consists of bacterial, archaeal, and fungal components that reside in mucosal surfaces of the gut, the airways, and the urogenital tract. Characterization of the symbiotic nature of the relationship between eukaryotic cells and the bacterial and archaeal components of the microbiota has revealed significant contributions in energy balance, bowel function, immunologic function, sensory perception, glycemic control, and blood pressure regulation. Elucidating the complex interactions between the microbiota and their associated epithelial, immune, and neural cells may provide mechanistic insights and a rational basis for our belief that dietary consumption of probiotic microorganisms and prebiotics produces health benefits.

中文翻译：

---

真核生物群交：益生元和益生菌对健康有益的潜在机制。

将益生元食品成分和益生菌微生物的饮食消费与健康益处联系起来的能力，部分取决于我们确定这些因素在多大程度上改变人类微生物组活性和/或结构的能力，以及识别真核细胞参与必需的能力。转导源自微生物组的信号。人类微生物组由细菌，古细菌和真菌组成，它们位于肠道，气道和泌尿生殖道的粘膜表面。真核细胞与微生物群的细菌和古细菌成分之间的共生关系的特征表明，在能量平衡，肠功能，免疫功能，感觉，血糖控制和血压调节方面有重要贡献。