当前位置: X-MOL 学术Annu. Rev. Genet. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The Bacillus and Myxococcus developmental networks and their transcriptional regulators.
Annual Review of Genetics ( IF 11.1 ) Pub Date : 2007-12-14 , DOI: 10.1146/annurev.genet.41.110306.130400
Lee Kroos 1
Affiliation  

Studies of endospore formation by Bacillus subtilis and fruiting body development of Myxococcus xanthus have revealed key features of regulatory networks that govern temporal and spatial gene expression in bacteria. In B. subtilis, sigma factor cascades, modulated by other types of transcription factors, regulate genes in two cell types that form and communicate with each other during starvation-induced sporulation. In M. xanthus, starving cells also send signals that alter gene expression, but the cascade to emerge so far involves transcription factors other than sigma factors. A hundred thousand cells coordinate their movements to build a fruiting body in which spores form. The two regulatory networks are compared, and questions that remain are identified.

中文翻译:

芽孢杆菌和粘球菌的发育网络及其转录调节因子。

对枯草芽孢杆菌的内生孢子形成和黄色葡萄球菌子实体发育的研究揭示了控制细菌中时空基因表达的调控网络的关键特征。在枯草芽孢杆菌中,由其他类型的转录因子调节的sigma因子级联可调节两种细胞类型中的基因,这些基因在饥饿诱导的孢子形成过程中相互形成并进行通讯。在X. xanthus中,挨饿的细胞也发送改变基因表达的信号,但是到目前为止出现的级联涉及转录因子而不是σ因子。十万个细胞协调其运动,以建立子实体,在其中形成孢子。比较这两个监管网络,并确定剩下的问题。
更新日期:2019-11-01
down
wechat
bug