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Prevalence and demographics of methicillin resistant Staphylococcus aureus in culturable skin and soft tissue infections in an urban emergency department.
BMC Emergency Medicine ( IF 2.5 ) Pub Date : 2007-10-31 , DOI: 10.1186/1471-227x-7-19
Christian H Jacobus 1 , Christopher J Lindsell , Sabrina D Leach , Gregory J Fermann , Amy Beth Kressel , Laura E Rue
Affiliation  

BACKGROUND The rising incidence of methicillin resistant Staph. aureus (MRSA) infections is a concern for emergency practitioners. While studies have examined MRSA in inpatients, few have focused on emergency department populations. We sought to describe predictors of MRSA skin infections in an emergency department population. METHODS This was a prospective observational cohort study conducted over three months in 2005. A convenience sample of patients with culturable skin infections presenting to a busy, urban emergency department was enrolled. Demographic and risk factor information was collected by structured interview. The predictive value of each risk factor for MRSA, as identified by culture, was tested using univariable logistic regression, and a multivariable predictive model was developed. RESULTS Patients were 43% black, 40% female and mean age was 39 years (SD 14 years). Of the 182 patients with cultures, prevalence of MRSA was 58% (95%CI 50% to 65%). Significant predictors of MRSA were youth, lower body mass index, sexual contact in the past month, presence of an abscess cavity, spontaneous infection, and incarceration. The multivariable model had a C-statistic of 0.73 (95%CI 0.67 to 0.79) with four significant variables: age, group living, abscess cavity, and sexual contact within one month. CONCLUSION In this population of emergency department patients, MRSA skin infection was related to youth, recent sexual contact, presence of abscess, low body mass index, spontaneity of infection, incarceration or contact with an inmate, and group home living.

中文翻译:

城市急诊科可培养皮肤和软组织感染中耐甲氧西林金黄色葡萄球菌的流行率和人口统计学。

背景 耐甲氧西林葡萄球菌的发病率不断上升。金黄色葡萄球菌 (MRSA) 感染是急诊医生关注的问题。虽然研究已经检查了住院患者的 MRSA,但很少有人关注急诊科人群。我们试图描述急诊科人群中 MRSA 皮肤感染的预测因素。方法 这是一项在 2005 年进行的为期三个月的前瞻性观察队列研究。招募了一个就诊于繁忙的城市急诊科的可培养皮肤感染患者的便利样本。通过结构化访谈收集人口统计学和风险因素信息。通过培养确定的 MRSA 的每个风险因素的预测值使用单变量逻辑回归进行测试,并开发了多变量预测模型。结果 患者中有 43% 是黑人,40% 女性,平均年龄为 39 岁(SD 14 岁)。在 182 名进行培养的患者中,MRSA 的患病率为 58%(95%CI 50% 至 65%)。MRSA 的重要预测因素是年轻、较低的体重指数、过去一个月的性接触、存在脓肿、自发感染和监禁。多变量模型的 C 统计量为 0.73(95%CI 0.67 至 0.79),有四个显着变量:年龄、群体生活、脓肿腔和一个月内的性接触。结论 在这群急诊科患者中,MRSA 皮肤感染与年轻、近期性接触、存在脓肿、低体重指数、自发性感染、监禁或与囚犯接触以及集体家庭生活有关。MRSA 的患病率为 58%(95%CI 50% 至 65%)。MRSA 的重要预测因素是年轻、较低的体重指数、过去一个月的性接触、存在脓肿、自发感染和监禁。多变量模型的 C 统计量为 0.73(95%CI 0.67 至 0.79),有四个显着变量:年龄、群体生活、脓肿腔和一个月内的性接触。结论 在这群急诊科患者中,MRSA 皮肤感染与年轻、近期性接触、存在脓肿、低体重指数、自发性感染、监禁或与囚犯接触以及集体家庭生活有关。MRSA 的患病率为 58%(95%CI 50% 至 65%)。MRSA 的重要预测因素是年轻、较低的体重指数、过去一个月的性接触、存在脓肿、自发感染和监禁。多变量模型的 C 统计量为 0.73(95%CI 0.67 至 0.79),有四个显着变量:年龄、群体生活、脓肿腔和一个月内的性接触。结论 在这群急诊科患者中,MRSA 皮肤感染与年轻、近期性接触、存在脓肿、低体重指数、自发性感染、监禁或与囚犯接触以及集体家庭生活有关。多变量模型的 C 统计量为 0.73(95%CI 0.67 至 0.79),有四个显着变量:年龄、群体生活、脓肿腔和一个月内的性接触。结论 在这群急诊科患者中,MRSA 皮肤感染与年轻、近期性接触、存在脓肿、低体重指数、自发性感染、监禁或与囚犯接触以及集体家庭生活有关。多变量模型的 C 统计量为 0.73(95%CI 0.67 至 0.79),有四个显着变量:年龄、群体生活、脓肿腔和一个月内的性接触。结论 在这群急诊科患者中,MRSA 皮肤感染与年轻、近期性接触、存在脓肿、低体重指数、自发性感染、监禁或与囚犯接触以及集体家庭生活有关。
更新日期:2019-11-01
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