Mild cognitive impairment (MCI) is a clinical syndrome thought to represent the transition between normal function and dementia. This review describes data that support the existence of such a transitional phase, outlines the heterogeneity of MCI and how that has influenced the evolving concept of MCI, and discusses the impact of heterogeneity on recent MCI clinical trials.

中文翻译：

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轻度认知障碍和痴呆。

轻度认知障碍（MCI）是一种临床综合征，被认为代表正常功能和痴呆症之间的过渡。这篇综述描述了支持这种过渡阶段存在的数据，概述了MCI的异质性以及它如何影响MCI不断发展的概念，并讨论了异质性对最新MCI临床试验的影响。