Suicide is the third leading cause of death in adolescence, and medically serious suicide attempts occur in approximately 3% of adolescents. This review examines a number of risk factors that contribute to suicidal behavior. A prior suicide attempt is one of the best predictors of both a repeat attempt and eventual completed suicide. Depression, disruptive behavior disorders, and substance-use disorders also place adolescents at high risk for suicidal behavior, with comorbidity further increasing risk. Research on families indicates that suicidal behavior is transmitted through families. Groups at high risk for suicidal behavior include gay, lesbian, and bisexual youths, incarcerated adolescents, and homeless/runaway teens. Although abnormalities in the serotonergic system have not been consistently linked to suicidal behavior, genetic and neurobiologic studies suggest that impulsive aggression may be the mechanism through which decreased serotonergic activity is related to suicidal behavior. Findings from prevention and intervention studies are modest and indicate the need for substantially more theory-driven treatment research.

中文翻译：

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企图并在青春期完成自杀。

自杀是青少年死亡的第三大主要原因，医学上严重的自杀企图发生在大约3％的青少年中。这篇综述检查了许多导致自杀行为的危险因素。先前的自杀尝试是重复尝试和最终自杀的最佳预测指标之一。抑郁症，破坏性行为障碍和物质使用障碍也使青少年处于自杀行为的高风险中，合并症进一步增加了风险。对家庭的研究表明，自杀行为是通过家庭传播的。自杀行为的高风险人群包括同性恋，女同性恋和双性恋青年，被监禁的青少年以及无家可归/失控的青少年。尽管血清素能系统异常并未一直与自杀行为有关，遗传和神经生物学研究表明，冲动攻击可能是血清素能活性降低与自杀行为相关的机制。预防和干预研究的结果并不充分，表明需要更多以理论为基础的治疗研究。