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Transcript profiling in host-pathogen interactions.
Annual Review of Phytopathology ( IF 10.2 ) Pub Date : 2007-05-08 , DOI: 10.1146/annurev.phyto.45.011107.143944
Roger P Wise 1 , Matthew J Moscou , Adam J Bogdanove , Steven A Whitham
Affiliation  

Using genomic technologies, it is now possible to address research hypotheses in the context of entire developmental or biochemical pathways, gene networks, and chromosomal location of relevant genes and their inferred evolutionary history. Through a range of platforms, researchers can survey an entire transcriptome under a variety of experimental and field conditions. Interpretation of such data has led to new insights and revealed previously undescribed phenomena. In the area of plant-pathogen interactions, transcript profiling has provided unparalleled perception into the mechanisms underlying gene-for-gene resistance and basal defense, host vs nonhost resistance, biotrophy vs necrotrophy, and pathogenicity of vascular vs nonvascular pathogens, among many others. In this way, genomic technologies have facilitated a system-wide approach to unifying themes and unique features in the interactions of hosts and pathogens.

中文翻译:

宿主-病原体相互作用中的转录谱分析。

使用基因组技术,现在有可能在整个发育或生化途径,基因网络以及相关基因的染色体位置及其推断的进化历史的背景下解决研究假设。通过一系列平台,研究人员可以在各种实验和现场条件下调查整个转录组。对这些数据的解释导致了新的见解,并揭示了先前无法描述的现象。在植物与病原体的相互作用领域,转录谱分析已为基因对基因的抗性和基础防御,宿主与非宿主抗性,生物营养与坏死以及血管与非血管病原体的致病性提供了无与伦比的认识。通过这种方式,
更新日期:2019-11-01
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