Forces are increasingly recognized as major regulators of cell structure and function, and the mechanical properties of cells are essential to the mechanisms by which cells sense forces, transmit them to the cell interior or to other cells, and transduce them into chemical signals that impact a spectrum of cellular responses. Comparison of the mechanical properties of intact cells with those of the purified cytoskeletal biopolymers that are thought to dominate their elasticity reveal the extent to which the studies of purified systems can account for the mechanical properties of the much more heterogeneous and complex cell. This review summarizes selected aspects of current work on cell mechanics with an emphasis on the structures that are activated in cell-cell contacts, that regulate ion flow across the plasma membrane, and that may sense fluid flow that produces low levels of shear stress.

中文翻译：

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细胞力学：整合细胞对机械刺激的反应。

越来越多的力量被认为是细胞结构和功能的主要调节者，细胞的机械性质对于细胞感知力，将力传递至细胞内部或其他细胞，并将其转化为影响细胞凋亡的化学信号的机制至关重要。细胞反应谱。将完整细胞的机械性能与认为主要控制其弹性的纯化细胞骨架生物聚合物的机械性能进行比较，揭示了对纯化系统的研究可解释异质性和复杂性细胞的机械性能的程度。这篇综述总结了当前细胞力学研究的某些方面，重点介绍了细胞间接触中激活的结构，这些结构可调节离子穿过质膜的流动，