In this review we discuss the major morphogenetic and regulative events that control myocardial progenitor cells from the time that they delaminate from the epiblast in the primitive streak to their differentiation into cardiomyocytes in the heart tube. During chick and mouse embryogenesis, myocardial progenitor cells go through four specific processes that are sequential but overlapping: specification of the cardiogenic mesoderm, determination of the bilaterally symmetric heart fields, patterning of the heart field, and finally cardiomyocyte differentiation and formation of the heart tube. We describe the morphological and molecular events that play a pivotal role in each of these four processes.

中文翻译：

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心脏场：从中胚层到心脏管。

在这篇综述中，我们讨论了控制心肌祖细胞的主要形态发生和调控事件，从它们从原始条纹的上皮细胞分层到在心管中分化为心肌细胞的时间。在雏鸡和小鼠胚胎发生过程中，心肌祖细胞经历四个相继但重叠的特定过程：确定中胚层的中胚层，确定双侧对称心脏场，确定心脏场的模式，最后进行心肌细胞分化和形成心管。我们描述了在这四个过程中的每一个都起关键作用的形态学和分子事件。