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Understanding circuit dynamics using the stomatogastric nervous system of lobsters and crabs.
Annual Review of Physiology ( IF 18.2 ) Pub Date : 2006-10-03 , DOI: 10.1146/annurev.physiol.69.031905.161516
Eve Marder 1 , Dirk Bucher
Affiliation  

Studies of the stomatogastric nervous systems of lobsters and crabs have led to numerous insights into the cellular and circuit mechanisms that generate rhythmic motor patterns. The small number of easily identifiable neurons allowed the establishment of connectivity diagrams among the neurons of the stomatogastric ganglion. We now know that (a) neuromodulatory substances reconfigure circuit dynamics by altering synaptic strength and voltage-dependent conductances and (b) individual neurons can switch among different functional circuits. Computational and experimental studies of single-neuron and network homeostatic regulation have provided insight into compensatory mechanisms that can underlie stable network performance. Many of the observations first made using the stomatogastric nervous system can be generalized to other invertebrate and vertebrate circuits.

中文翻译:

使用龙虾和螃蟹的胃胃神经系统了解回路动力学。

对龙虾和螃蟹的胃胃神经系统的研究已导致对产生节律性运动模式的细胞和电路机制的大量见解。少数易于识别的神经元可以在胃胃神经节的神经元之间建立连接图。我们现在知道,(a)神经调节物质通过改变突触强度和电压依赖性电导来重新配置电路动力学,(b)单个神经元可以在不同的功能电路之间切换。单神经元和网络稳态调节的计算和实验研究提供了对可作为稳定网络性能基础的补偿机制的见解。
更新日期:2019-11-01
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