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Preimplantation genetic diagnosis: an overview of socio-ethical and legal considerations.
Annual Review of Genomics and Human Genetics ( IF 8.7 ) Pub Date : 2006-05-27 , DOI: 10.1146/annurev.genom.7.080505.115753
Bartha M Knoppers 1 , Sylvie Bordet , Rosario M Isasi
Affiliation  

Preimplantation genetic diagnosis (PGD) permits the selection of embryos of a particular genotype prior to implantation. As a reproductive technology involving embryo selection, PGD has become associated with considerable controversy. This review examines some of the ethical, legal, and social issues raised by PGD. Relevant ethical considerations include the status of the embryo and the interests and duties of the parents. On a social policy level, considerations of access as well as the impact of this technology on families, women, and physician's duties also warrant consideration. An analysis of these issues in the context of using PGD for selecting embryos unaffected by a serious disorder and for sex selection is presented. We also present a brief survey of PGD-related regulatory schemes in several countries, including the United Kingdom and the United States.

中文翻译:

植入前遗传学诊断:社会伦理和法律考虑因素的概述。

植入前遗传学诊断(PGD)允许在植入前选择特定基因型的胚胎。作为涉及胚胎选择的生殖技术,PGD已引起相当大的争议。这篇评论检查了PGD提出的一些道德,法律和社会问题。相关的道德考虑因素包括胚胎的状态以及父母的利益和义务。从社会政策的角度出发,还应考虑访问的注意事项以及该技术对家庭,妇女和医生职责的影响。在使用PGD选择不受严重疾病影响的胚胎以及进行性别选择的背景下,对这些问题进行了分析。我们还对几个国家中与PGD相关的监管计划进行了简要调查,
更新日期:2019-11-01
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