The phenazines include upward of 50 pigmented, heterocyclic nitrogen-containing secondary metabolites synthesized by some strains of fluorescent Pseudomonas spp. and a few other bacterial genera. The antibiotic properties of these compounds have been known for over 150 years, but advances within the past two decades have provided significant new insights into the genetics, biochemistry, and regulation of phenazine synthesis, as well as the mode of action and functional roles of these compounds in the environment. This new knowledge reveals conservation of biosynthetic enzymes across genera but raises questions about conserved biosynthetic mechanisms, and sets the stage for improving the performance of phenazine producers used as biological control agents for soilborne plant pathogens.

中文翻译：

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荧光假单胞菌属中的吩嗪化合物。生物合成和调节。

吩嗪包括由某些荧光假单胞菌属菌株合成的多达50种有色杂环含氮次级代谢产物。和其他一些细菌属。这些化合物的抗生素特性已经有150多年的历史了，但是在过去的20年中的进步为吩嗪合成的遗传学，生物化学和调控以及这些化合物的作用方式和功能作用提供了重要的新见解。环境中的化合物。这一新知识揭示了整个属中生物合成酶的保守性，但提出了关于保守生物合成机制的问题，并为改善用作土壤传播植物病原体生物防治剂的吩嗪生产者的性能奠定了基础。