Vibrational spectroscopy (Infrared and Raman), and in particular micro-spectroscopy and micro-spectroscopic imaging has been used to characterize developmental changes in bone and other mineralized tissues, to monitor these changes in cell cultures, and to detect disease and drug-induced modifications. Examples of the use of infrared micro-spectroscopy and micro-spectroscopic imaging are discussed in this review.

中文翻译：

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矿化组织的红外光谱表征

振动光谱（红外和拉曼），特别是显微光谱和显微光谱成像已被用于表征骨骼和其他矿化组织的发育变化，监测细胞培养物中的这些变化，并检测疾病和药物诱导的改变. 本综述讨论了使用红外微光谱和微光谱成像的示例。