Abstract The article discusses how the metaphor of the BOOK OF LIFE was extended over time to cover the life cycle of the Human Genome Project from genetics to genomics. In particular, the focus is on the role of extendable metaphors in the debate on the Human Genome Project in three European newspapers, popular scientific journals and scientific and scholarly articles from 1990 to 2002. In these different domains of use, various parts of the metaphor were highlighted. The metaphor of BOOK OF LIFE was mainly used to justify the continuation of the gene research from gene sequencing to comparative genomics. Readily extendable metaphors, such as the BOOK OF LIFE, function as useful communicative tools both over time and across domains of use.

中文翻译：

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从测序到注释：将生命之书的隐喻从遗传学延伸到基因组学

摘要 本文讨论了生命之书的隐喻如何随着时间的推移而扩展，以涵盖从遗传学到基因组学的人类基因组计划的生命周期。特别是，从 1990 年到 2002 年，三个欧洲报纸、流行科学期刊以及科学和学术文章中关于人类基因组计划辩论的可扩展隐喻的作用尤其突出。在这些不同的使用领域中，隐喻的各个部分被突出显示。BOOK OF LIFE 的比喻主要是用来证明基因研究从基因测序到比较基因组学的延续。易于扩展的隐喻，例如生命之书，随着时间的推移和跨使用领域，都可以作为有用的交流工具。