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Malignant catatonia due to anti-NMDA-receptor encephalitis in a 17-year-old girl: case report.
Child and Adolescent Psychiatry and Mental Health ( IF 5.6 ) Pub Date : 2011-05-13 , DOI: 10.1186/1753-2000-5-15
Angèle Consoli 1 , Karine Ronen , Isabelle An-Gourfinkel , Martine Barbeau , Donata Marra , Nathalie Costedoat-Chalumeau , Delphine Montefiore , Philippe Maksud , Olivier Bonnot , Adrien Didelot , Zahir Amoura , Marie Vidailhet , David Cohen
Affiliation  

Anti-NMDA-Receptor encephalitis is a severe form of encephalitis that was recently identified in the context of acute neuropsychiatric presentation. Here, we describe the case of a 17-year-old girl referred for an acute mania with psychotic features and a clinical picture deteriorated to a catatonic state. Positive diagnosis of anti-NMDA-receptor encephalitis suggested specific treatment. She improved after plasma exchange and immunosuppressive therapy. Post-cognitive sequelae (memory impairment) disappeared within 2-year follow-up and intensive cognitive rehabilitation.

中文翻译:

一名 17 岁女孩因抗 NMDA 受体脑炎引起的恶性紧张症:病例报告。

抗 NMDA 受体脑炎是一种严重的脑炎形式,最近在急性神经精神病学表现的背景下被发现。在这里,我们描述了一个 17 岁女孩的案例,她因具有精神病特征的急性躁狂症而被转诊,并且临床图片恶化为紧张状态。抗 NMDA 受体脑炎的阳性诊断建议特殊治疗。她在血浆置换和免疫抑制治疗后好转。认知后后遗症(记忆障碍)在 2 年的随访和强化认知康复中消失。
更新日期:2019-11-01
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