Early embryonic imaging of cardiovascular development in mammalian models requires a method that can penetrate through and distinguish the many tissue layers with high spatial and temporal resolution. In this paper we evaluate the capability of Optical Coherence Tomography (OCT) technique for structural 3D embryonic imaging in mouse embryos at different stages of the developmental process ranging from 7.5 dpc up to 10.5 dpc. Obtained results suggest that the collected data is suitable for quantitative and qualitative measurements to assess cardiovascular function in mouse models, which is likely to expand our knowledge of the complexity of the embryonic heart, and its development into an adult heart.

中文翻译：

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哺乳动物胚胎早期发育过程的实时成像光学相干断层扫描

哺乳动物模型中心血管发育的早期胚胎成像需要一种能够穿透并区分具有高空间和时间分辨率的许多组织层的方法。在本文中，我们评估了光学相干断层扫描 (OCT) 技术在从 7.5 dpc 到 10.5 dpc 的发育过程的不同阶段对小鼠胚胎进行结构 3D 胚胎成像的能力。获得的结果表明，收集的数据适用于定量和定性测量，以评估小鼠模型中的心血管功能，这可能会扩展我们对胚胎心脏复杂性及其发育成成人心脏的认识。