Elimination of health disparities in the United States is a national health priority. Cardiovascular disease, diabetes, and obesity are key features of what is now referred to as the "cardiometabolic syndrome," which disproportionately affects racial/ethnic minority populations, including Native Hawaiians and other Pacific Islanders (NHOPI). Few studies have adequately characterized the cardiometabolic syndrome in high-risk populations such as NHOPI. The authors systematically assessed the existing literature on cardiometabolic disorders among NHOPI to understand the best approaches to eliminating cardiometabolic health disparities in this population. Articles were identified from database searches performed in PubMed and MEDLINE from January 1998 to December 2008; 43 studies were included in the review. There is growing confirmatory evidence that NHOPI are one of the highest-risk populations for cardiometabolic diseases in the United States. Most studies found increased prevalences of diabetes, obesity, and cardiovascular risk factors among NHOPI. The few experimental intervention studies found positive results. Methodological issues included small sample sizes, sample bias, inappropriate racial/ethnic aggregation of NHOPI with Asians, and a limited number of intervention studies. Significant gaps remain in the understanding of cardiometabolic health disparities among NHOPI in the United States. More experimental intervention studies are needed to examine promising approaches to reversing the rising tide of cardiometabolic health disparities in NHOPI.

中文翻译：

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夏威夷原住民和其他太平洋岛民的心脏代谢健康差异。

消除美国的健康差异是国家健康的优先事项。心血管疾病、糖尿病和肥胖症是现在被称为“心脏代谢综合征”的关键特征，它不成比例地影响种族/少数民族人口，包括夏威夷原住民和其他太平洋岛民 (NHOPI)。很少有研究充分描述 NHOPI 等高危人群的心脏代谢综合征。作者系统地评估了关于 NHOPI 心脏代谢紊乱的现有文献，以了解消除该人群心脏代谢健康差异的最佳方法。文章是从 1998 年 1 月至 2008 年 12 月在 PubMed 和 MEDLINE 中进行的数据库搜索中确定的；43 项研究被纳入该评价。越来越多的确证证据表明 NHOPI 是美国心脏代谢疾病风险最高的人群之一。大多数研究发现 NHOPI 中糖尿病、肥胖和心血管危险因素的患病率增加。少数实验性干预研究发现了积极的结果。方法学问题包括样本量小、样本偏倚、NHOPI 与亚洲人的种族/民族聚合不当，以及数量有限的干预研究。在美国 NHOPI 之间对心脏代谢健康差异的理解方面仍然存在重大差距。需要更多的实验性干预研究来检查有希望的方法来扭转 NHOPI 中心脏代谢健康差异的上升趋势。