We used an online word-monitoring paradigm to examine sentence processing in healthy seniors and frontotemporal dementia patients with progressive nonfluent aphasia (PNFA) or a nonaphasic disorder of social and executive functioning (SOC/EXEC). Healthy seniors were sensitive to morphosyntactic, major grammatical subcategory, and selection restriction violations in a sentence. PNFA patients were insensitive to grammatical errors, but showed reasonable sensitivity to thematic matrix violations, consistent with a differential grammatical processing impairment. By contrast, SOC/EXEC patients showed partial sensitivity to grammatical errors but were insensitive to thematic violations. These findings support a dissociation between grammatical and thematic components of sentence processing. Specifically, they are consistent with a grammatical processing deficit in PNFA patients, and impairment in the formation of a coherent thematic matrix in SOC/EXEC patients.

中文翻译：

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进行性非流利性失语和非失语性额颞叶痴呆的句法和主题成分

我们使用在线单词监控范式来检查健康老年人和患有进行性非流畅性失语症 (PNFA) 或社交和执行功能非失语症 (SOC/EXEC) 的额颞叶痴呆患者的句子处理。健康的老年人对句子中的形态句法、主要语法子类别和选择限制违规很敏感。PNFA 患者对语法错误不敏感，但对主题矩阵违规表现出合理的敏感性，与差异语法处理障碍一致。相比之下，SOC/EXEC 患者对语法错误表现出部分敏感，但对主题违规不敏感。这些发现支持句子处理的语法和主题成分之间的分离。具体来说，