The purpose of this paper is to review and evaluate measures of speech production that could be used to document effects of Deep Brain Stimulation (DBS) on speech performance, especially in persons with Parkinson disease (PD). A small set of evaluative criteria for these measures is presented first, followed by consideration of several speech physiology and speech acoustic measures that have been studied frequently and reported on in the literature on normal speech production, and speech production affected by neuromotor disorders (dysarthria). Each measure is reviewed and evaluated against the evaluative criteria. Embedded within this review and evaluation is a presentation of new data relating speech motions to speech intelligibility measures in speakers with PD, amyotrophic lateral sclerosis (ALS), and control speakers (CS). These data are used to support the conclusion that at the present time the slope of second formant transitions (F2 slope), an acoustic measure, is well suited to make inferences to speech motion and to predict speech intelligibility. The use of other measures should not be ruled out, however, and we encourage further development of evaluative criteria for speech measures designed to probe the effects of DBS or any treatment with potential effects on speech production and communication skills.

中文翻译：

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评估 DBS 对语音产生影响的措施

本文的目的是审查和评估可用于记录深部脑刺激 (DBS) 对言语表现的影响的言语产生测量，尤其是对帕金森病 (PD) 患者的影响。首先介绍这些测量的一小组评估标准，然后考虑一些经常研究并在文献中报道的关于正常言语产生和受神经运动障碍（构音障碍）影响的言语产生的言语生理学和言语声学指标. 每项措施都根据评估标准进行审查和评估。在此审查和评估中嵌入了与 PD、肌萎缩侧索硬化 (ALS) 和控制说话者 (CS) 的说话者的语音运动与语音清晰度测量相关的新数据的介绍。这些数据用于支持以下结论：目前第二共振峰转换的斜率（F2 斜率）是一种声学测量，非常适合推断语音运动和预测语音可懂度。然而，不应排除使用其他措施，我们鼓励进一步制定言语措施的评估标准，旨在探讨 DBS 的影响或任何对言语产生和沟通技巧有潜在影响的治疗。