This review highlights recent progress in developing DNA aptamers for personalized medicine, with more focus on in vivo studies for potential clinical applications. Examples include design of aptamers in combination with DNA nanostructures, nanomaterials, or microfluidic devices as diagnostic probes or therapeutic agents for cancers and other diseases. The use of aptamers as targeting agents in drug delivery is also covered. The advantages and future directions of such DNA aptamer-based technology for the continued development of personalized medicine are discussed.

中文翻译：

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用于个性化医疗的 DNA 适体技术。

本综述重点介绍了开发用于个性化医疗的 DNA 适配体的最新进展，更多地关注潜在临床应用的体内研究。例子包括设计适体与 DNA 纳米结构、纳米材料或微流体装置相结合，作为癌症和其他疾病的诊断探针或治疗剂。还涵盖了适体在药物递送中作为靶向剂的使用。讨论了这种基于 DNA 适配体的技术在个性化医疗的持续发展中的优势和未来方向。