Cytokines are critical mediators of inflammation and host defense. Cytokine production is regulated during transcription and post-transcription. Post-transcriptional regulation modifies mRNA stability and translation, allowing for the rapid and flexible control of gene expression, which is important for coordinating the initiation and resolution of inflammation. We review here a variety of post-transcriptional control mechanisms that regulate inflammation and discuss how these mechanisms are integrated to coordinate this essential process.

中文翻译：

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细胞因子mRNA的转录后调节控制炎症的发生和消退。

细胞因子是炎症和宿主防御的关键介质。在转录和转录后调节细胞因子的产生。转录后调控可调节mRNA的稳定性和翻译，从而可以快速灵活地控制基因表达，这对于协调炎症的引发和消退非常重要。我们在这里回顾各种调节炎症的转录后控制机制，并讨论如何整合这些机制以协调这一基本过程。