当前位置: X-MOL 学术Curr. Proteom. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Immunomics in Skin Cancer - Improvement in Diagnosis, Prognosis and Therapy Monitoring
Current Proteomics ( IF 0.8 ) Pub Date : 2013-10-01 , DOI: 10.2174/1570164611310030003
Amanda Bulman 1 , Monica Neagu , Carolina Constantin
Affiliation  

This review will focus on the elements of the skin’s immune system, immune cells and/or non-immune cells that support immune mechanisms, molecules with immune origin and/or immune functions that are involved in skin carcinogenesis. All these immune elements are compulsory in the development of skin tumors and/or sustainability of the neoplastic process. In this light, recent data gathered in this review will acknowledge all immune elements that contribute to skin tumorigenesis; moreover, they can serve as immune biomarkers. These immune markers can contribute to the diagnostic improvement, prognosis forecast, therapy monitoring, and even personalized therapeutical approach in skin cancer. Immune processes that sustain tumorigenesis in non-melanoma and melanoma skin cancers are described in the framework of recent data.

中文翻译:

皮肤癌免疫组学 - 诊断、预后和治疗监测的改进

本综述将重点关注皮肤免疫系统的要素、支持免疫机制的免疫细胞和/或非免疫细胞、具有免疫起源和/或与皮肤癌发生有关的免疫功能的分子。所有这些免疫元素对于皮肤肿瘤的发展和/或肿瘤过程的可持续性都是必不可少的。有鉴于此,本综述中收集的最新数据将承认所有导致皮肤肿瘤发生的免疫因素;此外,它们可以作为免疫生物标志物。这些免疫标志物有助于皮肤癌的诊断改进、预后预测、治疗监测,甚至个性化治疗方法。在最近的数据框架中描述了在非黑色素瘤和黑色素瘤皮肤癌中维持肿瘤发生的免疫过程。
更新日期:2013-10-01
down
wechat
bug