Cyanobacteria have developed various response mechanisms in long evolution to sense and adapt to external or internal changes under abiotic stresses. The signal transduction system of a model cyanobacterium Synechocystis sp. PCC 6803 includes mainly two-component signal transduction systems of eukaryotic-type serine/threonine kinases (STKs), on which most have been investigated at present. These two-component systems play a major role in regulating cell activities in cyanobacteria. More and more co-regulation and crosstalk regulations among signal transduction systems had been discovered due to increasing experimental data, and they are of great importance in corresponding to abiotic stresses. However, mechanisms of their functions remain unknown. Nevertheless, the two signal transduction systems function as an integral network for adaption in different abiotic stresses. This review summarizes available knowledge on the signal transduction network in Synechocystis sp. PCC 6803 and biotechnological implications under various stresses, with focuses on the co-regulation and crosstalk regulations among various stress-responding signal transduction systems.

蓝细菌在长期的进化过程中已经发展出各种反应机制，以感知并适应非生物胁迫下的外部或内部变化。模型蓝藻集胞藻的信号转导系统sp。PCC 6803主要包括真核型丝氨酸/苏氨酸激酶（STK）的两组分信号转导系统，目前已对其进行了研究。这两个组成部分的系统在调节蓝细菌的细胞活性中起主要作用。由于实验数据的增加，在信号转导系统之间发现了越来越多的共同调节和串扰调节，它们在应对非生物胁迫方面具有重要意义。但是，其功能机制仍然未知。尽管如此，这两个信号转导系统还是一个不可或缺的网络，可以适应不同的非生物胁迫。这篇综述总结了有关囊突藻信号转导网络的可用知识sp。PCC 6803及其在各种压力下的生物技术意义，着重于各种压力响应信号转导系统之间的共同调节和串扰调节。