The versatility and sensitivity of the quadrupole ion trap tandem mass spectrometer has been applied to the determination of polychlorodibenzo-p-dioxins (PCDDs) and polychlorodibenzofurans (PCDFs), and of polychlorinated biphenyls (PCBs). A brief introduction to the theory of ion confinement in a quadrupole ion trap permits discussion of ion trajectory stability, mass-selective ion ejection, the frequencies of ion motion, and the role of resonant excitation of ion motion. The tandem mass spectrometric examination of PCDDs and PCDFs eluting and co-eluting from a gas chromatographic column is described. Illustrative examples are given of the analysis of field samples containing PCDDs and PCDFs. A comparison is presented of the performance of each of a quadrupole ion trap tandem mass spectrometer, a triple stage quadrupole mass spectrometer, and a sector instrument of relatively high mass resolution for the determination of PCDDs and PCDFs. This comparison is made with respect to instrument tuning, calibration plots, detection limits, ion signals at low concentration, relative response factors, ionization cross-sections, and the examination of field samples. The application of quadrupole ion trap tandem mass spectrometry to the examination of PCBs is focused upon those PCB congeners that have the greatest toxicity. 39 congeners of the total of 209 PCB congeners have been identified as having the greatest toxicities. Chemical ionization has been used for the determination of co-eluting congeners #77 and #110 where the toxicity of the former is much greater than that of the latter. An analytical protocol, based on the variation of molecular ion fragmentation according to the degree (or absence) of chlorine ortho-substitution, has been proposed for distinguishing between toxic and nontoxic PCB congeners.

中文翻译：

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用四极杆离子阱气相色谱-质谱法测定二恶英/呋喃和多氯联苯。

四极离子阱串联质谱仪的多功能性和灵敏度已用于测定多氯二苯并-对-二恶英（PCDD）和多氯二苯并呋喃（PCDF）和多氯联苯（PCB）。对四极离子阱中离子约束理论的简要介绍，可以讨论离子轨迹的稳定性，质量选择性离子喷射，离子运动的频率以及离子运动的共振激发的作用。描述了从气相色谱柱洗脱和共洗脱的PCDD和PCDF的串联质谱检测。给出了分析含有PCDDs和PCDFs的田间样品的示例。比较了四极离子阱串联质谱仪，三级四极质谱仪各自的性能，以及具有相对较高质量分辨率的部门仪器，用于测定PCDD和PCDF。在仪器调整，校准图，检测极限，低浓度离子信号，相对响应因子，电离截面和现场样品检查方面进行了比较。四极杆离子阱串联质谱在PCB的检测中的应用集中于那些毒性最大的PCB同系物。在总共209种PCB同类产品中，有39种同类产品被确认具有最大的毒性。化学电离已用于测定共洗脱同类物＃77和＃110，其中前者的毒性远大于后者。分析协议，