The recent emergence of optical imaging has brought forth a unique challenge for chemists: development of new biocompatible dyes that fluoresce in the near-infrared (NIR) region for optimal use in biomedical applications. This review describes the synthesis of NIR dyes and the design of probes capable of noninvasively imaging molecular events in small animal models.

中文翻译：

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近红外染料：光学分子成像中的探针开发和应用。

最近出现的光学成像给化学家带来了独特的挑战：开发在近红外 (NIR) 区域发荧光的新型生物相容性染料，以便在生物医学应用中发挥最佳作用。这篇综述描述了 NIR 染料的合成和能够在小动物模型中对分子事件进行非侵入性成像的探针的设计。