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Unique divergence of the breast cancer 2 (BRCA2) gene in Neanderthals
Hereditas ( IF 2.7 ) Pub Date : 2018-11-03 , DOI: 10.1186/s41065-018-0073-5
Pawel Michalak 1, 2, 3 , Lin Kang 2
Affiliation  

Unique divergence of the BRCA2, a tumor suppressor gene, in Neanderthals relative to other primates, including modern humans, is highlighted. This divergence with potentially pathogenic consequences raises a question about cancer susceptibility in the archaic species that was replaced by modern humans about 40,000 years ago.

中文翻译:

尼安德特人乳腺癌 2 (BRCA2) 基因的独特差异

尼安德特人的肿瘤抑制基因 BRCA2 与其他灵长类动物(包括现代人类)的独特差异得到了强调。这种具有潜在致病性后果的差异引发了一个关于大约 40,000 年前被现代人类取代的古老物种的癌症易感性的问题。
更新日期:2018-11-03
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