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Protein Nanoparticles as Multifunctional Biocatalysts and Health Assessment Sensors.
Current Opinion in Chemical Engineering ( IF 6.6 ) Pub Date : 2016-08-01 , DOI: 10.1016/j.coche.2016.08.016
Maryam Raeeszadeh-Sarmazdeh 1 , Emily Hartzell 1 , J Vincent Price 1 , Wilfred Chen 1
Affiliation  

The use of protein nanoparticles for biosensing, biocatalysis and drug delivery has exploded in the last few years. The ability of protein nanoparticles to self-assemble into predictable, monodisperse structures is of tremendous value. The unique properties of protein nanoparticles such as high stability, and biocompatibility, along with the potential to modify them led to development of novel bioengineering tools. Together, the ability to control the interior loading and external functionalities of protein nanoparticles makes them intriguing nanodevices. This review will focus on a number of recent examples of protein nanoparticles that have been engineered towards imparting the particles with biocatalytic or biosensing functionality.

中文翻译:

蛋白质纳米颗粒作为多功能生物催化剂和健康评估传感器。

在过去的几年中,蛋白质纳米颗粒在生物传感,生物催化和药物输送中的应用激增。蛋白质纳米颗粒自组装成可预测的单分散结构的能力具有巨大的价值。蛋白质纳米颗粒的独特特性,例如高稳定性和生物相容性,以及修饰它们的潜力,导致了新型生物工程工具的开发。总之,控制蛋白质纳米颗粒内部内部负载和外部功能的能力使其成为吸引人的纳米设备。这篇综述将集中在蛋白质纳米粒子的许多最新实例上,这些蛋白质纳米粒子已被设计为赋予这些粒子以生物催化或生物传感功能。
更新日期:2016-09-04
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