Berries and their phytochemicals have well documented chemopreventive roles, but understanding their ability to regulate cancer immunology is only beginning to be explored. The literature, including human studies, suggests that berry components can modulate our immune system to delay cancer development. Moreover, their wide spectrum of phytochemicals suggests that they might influence the functions of multiple immune cells and different aspects of cancer immunity. Cancer immune-therapies are showing promise for some types of cancer because they boost T cells' ability to recognize tumor cells - an essential prelude to destruction. Recognition occurs after dendritic cells present antigen, such as tumor antigen, to T cells, generating an adaptive response. Therefore, the potential of berries to aid cancer immune-therapies by, for example, regulating dendritic cells, warrants further investigation in animal and human studies. More information is also needed about berries' effects on the entire spectrum of immunity so that a comprehensive view can inform efforts to use berries to enhance immune responses during cancer prevention and treatment. This review summarizes the effects of berries as anti-tumor agents from the immunological perspective in tumor-bearing animals and humans.

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用浆果预防癌症的免疫学观点

浆果及其植物化学物质具有良好的化学预防作用，但了解它们调节癌症免疫学的能力才刚刚开始探索。包括人类研究在内的文献表明，浆果成分可以调节我们的免疫系统以延缓癌症的发展。此外，它们广泛的植物化学物质表明它们可能影响多种免疫细胞的功能和癌症免疫的不同方面。癌症免疫疗法对某些类型的癌症显示出希望，因为它们提高了 T 细胞识别肿瘤细胞的能力——这是破坏的必要前奏。识别发生在树突细胞向 T 细胞呈递抗原（如肿瘤抗原）后，产生适应性反应。因此，浆果具有帮助癌症免疫疗法的潜力，例如，调节树突细胞，值得在动物和人类研究中进一步研究。还需要更多关于浆果对整个免疫范围的影响的信息，以便全面了解在癌症预防和治疗过程中使用浆果增强免疫反应的努力。本综述从免疫学角度总结了浆果作为抗肿瘤剂在荷瘤动物和人类中的作用。