Two novel oxidovanadium(IV) complexes with a new bidentate (O- and N-) imine-based ligand 2-((E)-(6-fluorobenzo[d]thiazol-2-ylimino)methyl)-6-methoxyphenol (HL) were synthesized under in situ experimental condition where VOSO₄ acts as a kinetic template in the ratio 2 : 1 (L : M) and mixed ligand complex using 1,10-phenanthroline (phen) in 1 : 1 : 1 (L : M : phen) ratio. The synthesized compounds were structurally characterized by microanalysis, magnetic susceptibility, FTIR, electronic spectra, TG/DTA, ESR, and molar conductance studies. Based on the spectral studies, the complexes have the general composition [VO(L)₂] (C₁) and [VO(L)phen] (C₂) in a square pyramid geometrical fashion. The synthesized compounds were primarily screened for their in vitro growth inhibiting activity against different strains of bacteria, namely, E. coli, B. subtilis, S. aureus, and P. aeruginosa by the disc diffusion method. Also, the antifungal activity was determined against C. albicans and A. niger by the Bateman poisoned technique. The in vitro antioxidant activity of all the compounds was determined by DPPH free radical-scavenging assay. Intercalative mode of DNA-binding properties of the oxidovanadium(IV) complexes with calf-thymus DNA (CT-DNA) was investigated using UV, fluorescence spectra, and viscosity measurements.

中文翻译：

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2-（（E）-（6-氟苯并[d]噻唑-2-ylimino）甲基）-6-甲氧基苯酚的钒钒（IV）配合物的合成，表征及其抗菌，抗氧化剂和DNA结合研究。

两个新的氧化钒（IV）配合物与新的基于二齿（O-和N-）亚胺的配体2-（（E）-（6-氟苯并[d]噻唑-2-ylimino）甲基）-6-甲氧基苯酚（HL ）是在原位实验条件下合成的，其中VOSO ₄以2：1（L：M）的比例作为动力学模板，并使用1,10-菲咯啉（phen）以1：1：1（L：M）混合配体复合物：phen）比。通过微分析，磁化率，FTIR，电子光谱，TG / DTA，ESR和摩尔电导研究对合成的化合物进行结构表征。根据光谱研究，配合物的一般组成为[VO（L）₂ ]（C ₁）和[VO（L）phen]（C ₂）以方形金字塔的几何方式呈现。首先通过圆盘扩散法筛选合成的化合物对不同菌株的细菌，即大肠杆菌，枯草芽孢杆菌，金黄色葡萄球菌和铜绿假单胞菌的体外生长抑制活性。同样，通过贝特曼中毒技术测定了对白色念珠菌和黑曲霉的抗真菌活性。在体外通过DPPH清除自由基法测定所有化合物的抗氧化活性。使用紫外线，荧光光谱和粘度测量研究了氧化钒（IV）与小牛胸腺DNA（CT-DNA）的DNA结合特性的插入模式。