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Development, functional organization, and evolution of vertebrate axial motor circuits.
Neural Development ( IF 3.6 ) Pub Date : 2018-06-01 , DOI: 10.1186/s13064-018-0108-7
Kristen P D'Elia 1 , Jeremy S Dasen 1
Affiliation  

Neuronal control of muscles associated with the central body axis is an ancient and essential function of the nervous systems of most animal species. Throughout the course of vertebrate evolution, motor circuits dedicated to control of axial muscle have undergone significant changes in their roles within the motor system. In most fish species, axial circuits are critical for coordinating muscle activation sequences essential for locomotion and play important roles in postural correction. In tetrapods, axial circuits have evolved unique functions essential to terrestrial life, including maintaining spinal alignment and breathing. Despite the diverse roles of axial neural circuits in motor behaviors, the genetic programs underlying their assembly are poorly understood. In this review, we describe recent studies that have shed light on the development of axial motor circuits and compare and contrast the strategies used to wire these neural networks in aquatic and terrestrial vertebrate species.

中文翻译:

脊椎动物轴向运动回路的发展,功能组织和演变。

与身体中枢轴相关的肌肉的神经元控制是大多数动物物种神经系统的古老且必不可少的功能。在整个脊椎动物进化过程中,专用于控制轴向肌肉的马达电路在马达系统中的作用发生了重大变化。在大多数鱼类中,轴向回路对于协调运动必需的肌肉激活序列至关重要,并且在姿势矫正中起重要作用。在四脚架中,轴向回路已演化出对于陆地生命必不可少的独特功能,包括维持脊柱的排列和呼吸。尽管轴向神经回路在运动行为中起着不同的作用,但对其组装基础的遗传程序知之甚少。在这篇评论中
更新日期:2020-04-22
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