HIV-infected patients have an increased risk of renal disease. Current first-line antiretroviral therapy contains tenofovir disoproxil fumarate (TDF), which has nephrotoxic potential, characterised by proximal tubular cell injury. This may result in acute kidney injury, chronic kidney disease or partial or complete Fanconi syndrome.

中文翻译：

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南非 HIV 感染患者急性肾损伤的方法。

HIV感染者患肾病的风险增加。目前的一线抗逆转录病毒疗法含有富马酸替诺福韦二吡呋酯（TDF），它具有肾毒性潜力，以近端肾小管细胞损伤为特征。这可能导致急性肾损伤、慢性肾病或部分或完全范可尼综合征。