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Altered expression of microRNA during fracture healing in diabetic rats.
Bone & Joint Research ( IF 4.6 ) Pub Date : 2018-2-14 , DOI: 10.1302/2046-3758.72.bjr-2017-0082.r1
S Takahara 1 , S Y Lee 2 , T Iwakura 1 , K Oe 1 , T Fukui 1 , E Okumachi 1 , T Waki 1 , M Arakura 1 , Y Sakai 3 , K Nishida 1 , R Kuroda 1 , T Niikura 4
Affiliation  

Diabetes mellitus (DM) is known to impair fracture healing. Increasing evidence suggests that some microRNA (miRNA) is involved in the pathophysiology of diabetes and its complications. We hypothesized that the functions of miRNA and changes to their patterns of expression may be implicated in the pathogenesis of impaired fracture healing in DM.

中文翻译:

糖尿病大鼠骨折愈合过程中microRNA的表达改变。

已知糖尿病(DM)会损害骨折愈合。越来越多的证据表明,某些微RNA(miRNA)与糖尿病及其并发症的病理生理有关。我们假设,miRNA的功能及其表达模式的改变可能与DM骨折愈合受损的发病机制有关。
更新日期:2020-08-21
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