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Numerical simulations of magnetic resonance elastography using finite element analysis with a linear heterogeneous viscoelastic model
Journal of Visualization ( IF 1.7 ) Pub Date : 2017-06-10 , DOI: 10.1007/s12650-017-0436-4
Sunao Tomita 1 , Hayato Suzuki 1 , Itsuro Kajiwara 1 , Gen Nakamura 2 , Yu Jiang 3 , Mikio Suga 4 , Takayuki Obata 5 , Shigeru Tadano 1
Affiliation  

Magnetic resonance elastography (MRE) is a technique to identify the viscoelastic moduli of biological tissues by solving the inverse problem from the displacement field of viscoelastic wave propagation in a tissue measured by MRI. Because finite element analysis (FEA) of MRE evaluates not only the viscoelastic model for a tissue but also the efficiency of the inversion algorithm, we developed FEA for MRE using commercial software called ANSYS, the Zener model for displacement field of a wave inside tissue, and an inversion algorithm called the modified integral method. The profile of the simulated displacement field by FEA agrees well with the experimental data measured by MRE for gel phantoms. Similarly, the value of storage modulus (i.e., stiffness) recovered using the modified integral method with the simulation data is consistent with the value given in FEA. Furthermore, applying the suggested FEA to a human liver demonstrates the effectiveness of the present simulation scheme.Graphical abstract

中文翻译:

使用线性非均质粘弹性模型进行有限元分析的磁共振弹性成像数值模拟

磁共振弹性成像 (MRE) 是一种通过解决 MRI 测量的组织中粘弹性波传播的位移场的反问题来识别生物组织粘弹性模量的技术。由于 MRE 的有限元分析 (FEA) 不仅评估组织的粘弹性模型,还评估反演算法的效率,我们使用名为 ANSYS 的商业软件开发了 MRE 的 FEA,即组织内波位移场的齐纳模型,以及一种称为修正积分法的反演算法。FEA 模拟的位移场分布与 MRE 测量的凝胶体模的实验数据非常吻合。同样,储能模量的值(即,刚度)使用修正积分法与模拟数据恢复,与 FEA 中给出的值一致。此外,将建议的有限元分析应用于人类肝脏证明了本模拟方案的有效性。图形摘要
更新日期:2017-06-10
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