The exact aetiology and pathogenesis of microdamage-induced long bone fractures remain unknown. These fractures are likely to be the result of inadequate bone remodelling in response to damage. This study aims to identify an association of osteocyte apoptosis, the presence of osteocytic osteolysis, and any alterations in sclerostin expression with a fracture of the third metacarpal (Mc-III) bone of Thoroughbred racehorses.

中文翻译：

---

与纯种赛马的第三掌骨应力性骨折相关的硬化素增加。

微损伤引起的长骨骨折的确切病因和发病机制仍然未知。这些骨折很可能是由于对损伤的不充分的骨骼重塑造成的。这项研究的目的是确定与纯种赛马的第三掌骨（Mc-III）骨骨折相关的骨细胞凋亡，骨细胞溶骨的存在以及硬化蛋白表达的任何改变。