Nanoparticles are used widely in our lives, but the understanding of their impacts on human and environmental health is still limited, at least due in part to the fact that nanoparticles are mixtures. This review describes that "nanotoxicity" is actually a test of the overall effect of a nanoparticle mixture: starting materials for nanoparticle preparation, surface coating agents, surface reaction-generated species, and transformed byproducts of the nanoparticle in biological and environmental media, as well as variations of the intrinsic nanoparticle structures.

中文翻译：

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纳米颗粒被视为毒理学研究的混合物。

纳米粒子在我们的生活中被广泛使用，但是对它们对人类和环境健康的影响的理解仍然有限，至少部分是由于纳米粒子是混合物这一事实。这篇评论描述了“纳米毒性”实际上是对纳米颗粒混合物整体效果的测试：纳米颗粒制备的原材料，表面涂层剂，表面反应生成的物种以及在生物和环境介质中纳米颗粒的转化副产物，以及作为固有纳米粒子结构的变化。