The pathophysiological role of detrusor overactivity (DO) in the bladder, which is commonly observed in various bladder diseases, is not well understood. DO appears in bladder outlet obstruction (BOO), and may continue even after subsequent deobstruction. DO therefore provides an excellent opportunity to observe molecular biological changes.

中文翻译：

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梗阻后膀胱出口梗阻大鼠逼尿肌过度活动的膀胱中近乎标准化的基因表达谱。

膀胱中逼尿肌过度活动（DO）的病理生理作用，在各种膀胱疾病中普遍观察到的，尚未被很好地理解。DO出现在膀胱出口梗阻（BOO）中，甚至在随后的梗阻后仍可能持续。因此，溶解氧提供了观察分子生物学变化的绝好机会。