当前位置: X-MOL 学术Pediatr. Allergy Immunol. Pulmonol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Diet, Lung Function, and Asthma Exacerbations in Puerto Rican Children.
Pediatric Allergy, Immunology, and Pulmonology ( IF 0.9 ) Pub Date : 2017-12-28 , DOI: 10.1089/ped.2017.0803
Yueh-Ying Han 1 , Erick Forno 1 , Maria Alvarez 2 , Angel Colón-Semidey 2 , Edna Acosta-Perez 2 , Glorisa Canino 2 , Juan C Celedón 1
Affiliation  

Changes in dietary patterns may partly explain the epidemic of asthma in industrialized countries. The objective of this study was to examine the relationship between dietary patterns and lung function and asthma exacerbations in Puerto Rican children. This is a case-control study of 678 Puerto Rican children (ages 6-14 years) in San Juan (Puerto Rico). All participants completed a respiratory health questionnaire and a 75-item food frequency questionnaire. Food items were aggregated into 7 groups: fruits, vegetables, grains, protein, dairy, fats, and sweets. Logistic regression was used to evaluate consumption frequency of each group and asthma. Based on the results, a dietary score was created [range from -2 (unhealthy diet: high consumption of dairy and sweets, low consumption of vegetables and grains) to 2 (healthy diet: high consumption of vegetables and grains and low consumption of dairy and sweet)]. Multivariable linear or logistic regression was used to assess the relationship between dietary score and lung function or asthma exacerbations. After adjustment for covariates, a healthier diet (each 1-point increment in dietary score) was associated with significantly higher %predicted forced expiratory volume in the first second (FEV1) and %predicted forced vital capacity (FVC) in control subjects. Dietary pattern alone was not associated with asthma exacerbations, but children with an unhealthy diet and vitamin D insufficiency (plasma 25(OH)D <30 ng/mL) had higher odds of ≥1 severe asthma exacerbation [odds ratio (OR) = 3.4, 95% confidence interval (CI) = 1.5-7.5] or ≥1 hospitalization due to asthma (OR = 3.9, 95% CI = 1.6-9.8, OR = 3.4, 95% CI = 1.5-7.5) than children who ate a healthy diet and were vitamin D sufficient. A healthy diet, with frequent consumption of vegetables and grains and low consumption of dairy products and sweets, was associated with higher lung function (as measured by FEV1 and FVC). Vitamin D insufficiency, together with an unhealthy diet, may have detrimental effects on asthma exacerbations in children.

中文翻译:

波多黎各儿童的饮食,肺功能和哮喘急性发作。

饮食结构的变化可能部分解释了工业化国家中哮喘的流行。这项研究的目的是检查波多黎各儿童的饮食模式与肺功能和哮喘加重之间的关系。这是对圣胡安(波多黎各)的678名波多黎各儿童(6至14岁)的病例对照研究。所有参与者均完成了呼吸健康问卷和75项食物频率问卷。食品分为7类:水果,蔬菜,谷物,蛋白质,乳制品,脂肪和糖果。使用逻辑回归分析评估每组和哮喘的消费频率。根据结果​​,制定了饮食评分(范围从-2(不健康饮食:大量食用奶制品和甜食,少量蔬菜和谷物)到2(健康饮食:蔬菜和谷物的高消耗量以及乳制品和甜食的低消耗量]]。多变量线性或逻辑回归用于评估饮食评分与肺功能或哮喘加重之间的关系。在对协变量进行调整之后,较健康的饮食(饮食评分每增加1分)与对照组受试者在第一秒内预测的强制呼气量(FEV1)和预测的强制肺活量(FVC)显着较高的百分比相关。单独的饮食模式与哮喘发作没有关系,但是饮食不健康和维生素D不足(血浆25(OH)D <30 ng / mL)的儿童发生严重哮喘发作的几率≥1[赔率(OR)= 3.4 ,95%置信区间(CI)= 1.5-7.5]或≥1因哮喘住院(OR = 3.9,95%CI = 1.6-9.8,OR = 3.4,95%CI = 1.5-7。5)比饮食健康且维生素D足够的儿童。健康的饮食习惯,经常食用蔬菜和谷物,而乳制品和甜食的消费量较低,与肺功能较高相关(如FEV1和FVC所测)。维生素D缺乏,加上不健康的饮食,可能对儿童哮喘发作加重有害。
更新日期:2019-11-01
down
wechat
bug