In recent years there have been an increasing number of in vitro and in vivo studies that show positive results regarding antimicrobial photodynamic therapy (aPDT) used in dentistry. These include applications in periodontics, endodontics, and mucosal infections caused by bacteria present as biofilms. Antimicrobial photodynamic therapy is a therapy based on the combination of a non-toxic photosensitizer (PS) and appropriate wavelength visible light, which in the presence of oxygen is activated to produce reactive oxygen species (ROS). ROS induce a series of photochemical and biological events that cause irreversible damage leading to the death of microorganisms. Many light-absorbing dyes have been mentioned as potential PS for aPDT and different wavelengths have been tested. However, there is no consensus on a standard protocol yet. Thus, the goal of this review was to summarize the results of research on aPDT in dentistry using the PubMed database focusing on recent studies of the effectiveness aPDT in decreasing microorganisms and microbial biofilms, and also to describe aPDT effects, mechanisms of action and applications.

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抗菌光动力疗法（aPDT）在牙科中的应用：批判性评论

近年来，越来越多的体外和体内研究显示了牙科中使用的抗菌光动力疗法 (aPDT) 的积极结果。这些包括在牙周病学、牙髓病学和由以生物膜形式存在的细菌引起的粘膜感染中的应用。抗菌光动力疗法是一种基于无毒光敏剂 (PS) 和适当波长的可见光组合的疗法，在有氧的情况下，可见光被激活以产生活性氧 (ROS)。ROS 诱导一系列光化学和生物事件，造成不可逆转的损害，导致微生物死亡。许多吸光染料被认为是 aPDT 的潜在 PS，并且已经测试了不同的波长。然而，目前还没有就标准协议达成共识。因此，