Heart failure (HF) is associated with significant morbidity and mortality and an increasing economic burden. The persistence of HF's risk factors, coupled with an aging population, also leads to an increase in its incidence and prevalence. It is well established that sympathetic hyperactivity and parasympathetic withdrawal are instrumental in the development and worsening of HF. Therefore, restoring autonomic balance to the cardiovascular system is an attractive therapeutic approach. The following is a review of current clinical trials of device-based autonomic regulation therapy in the management of HF with a reduced ejection fraction.

中文翻译：

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用于心力衰竭的自主调节疗法的设备，其射血分数降低。

心力衰竭（HF）与明显的发病率和死亡率以及日益增加的经济负担相关。HF的危险因素的持续存在，加上人口老龄化，也导致其发病率和患病率增加。众所周知，交感神经亢进和副交感神经退缩在HF的发生和恶化中起重要作用。因此，恢复心血管系统的自主平衡是一种有吸引力的治疗方法。以下是在减少射血分数的HF治疗中基于设备的自主调节疗法的当前临床试验的综述。