Two-dimensional speckle tracking echocardiography represents a novel, simple, and reproducible technique for the estimation of left ventricular myocardial deformation (strain) and the evaluation of left ventricular twist mechanics. During the last few years, its clinical and prognostic implications in cardiomyopathies and hypertrophic cardiomyopathy (HCM), in particular, have been rapidly increasing. Reduced global longitudinal strain is associated with more severe disease and confers an increased risk for major cardiac events, independently of other clinical and echocardiographic risk factors. Left ventricular dyssynchrony also seems promising as a risk factor for sudden cardiac events. With respect to left atrial mechanics, left atrial reservoir, conduit, and contractile strain may also confer an increased prognostic value for atrial fibrillation, major cardiac events, and even sudden death. Although right ventricular global longitudinal strain is impaired in HCM compared with healthy controls and individuals with physiological hypertrophy, its prognostic significance is currently unknown. Conclusively, 2-dimensional speckle tracking imaging seems promising for HCM. However, future studies are needed to incorporate this new imaging technique in the standard evaluation of an HCM individual.

中文翻译：

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二维斑点追踪超声心动图在肥厚型心肌病中的预后意义：当前和将来的观点。

二维散斑跟踪超声心动图代表了一种新颖，简单且可重现的技术，用于评估左心室心肌变形（应变）和评估左心室扭曲力学。在过去的几年中，其在心肌病和肥厚性心肌病（HCM）中的临床和预后意义尤其迅速增加。与其他临床和超声心动图危险因素无关，总体纵向张力的降低与更严重的疾病相关，并且增加了发生重大心脏事件的风险。左心室不同步似乎也有望成为突发心脏事件的危险因素。关于左心房力学，左心房水库，导管，收缩性应变也可能增加房颤，主要心脏事件甚至猝死的预后价值。尽管与健康对照组和具有生理性肥大的个体相比，HCM中右心室整体纵向应变受损，但其预后意义目前未知。最终，二维散斑跟踪成像对于HCM似乎很有希望。但是，需要进行进一步的研究以将这种新的成像技术纳入HCM个人的标准评估中。二维斑点跟踪成像对于HCM似乎很有希望。但是，需要进行进一步的研究以将这种新的成像技术纳入HCM个人的标准评估中。二维斑点跟踪成像对于HCM似乎很有希望。但是，需要进行进一步的研究以将这种新的成像技术纳入HCM个人的标准评估中。