To establish a model to enrich and characterize stem-like cells from murine normal liver and hepatocellular carcinoma (HCC) cell lines and to further investigate stem-like cell association with epithelial-to-mesenchymal transition (EMT).

中文翻译：

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鼠肝细胞癌衍生的干细胞显示出上皮到间质的可塑性。

建立一个模型来富集和表征鼠类正常肝和肝细胞癌（HCC）细胞系中的干样细胞，并进一步研究干样细胞与上皮到间充质转化（EMT）的关联。