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Adipose-derived stromal cell in regenerative medicine: A review.
World Journal of Stem Cells ( IF 4.1 ) Pub Date : 2017-9-21 , DOI: 10.4252/wjsc.v9.i8.107
Reza Tabatabaei Qomi 1 , Mohsen Sheykhhasan 1
Affiliation  

The application of appropriate cell origin for utilizing in regenerative medicine is the major issue. Various kinds of stem cells have been used for the tissue engineering and regenerative medicine. Such as, several stromal cells have been employed as treat option for regenerative medicine. For example, human bone marrow-derived stromal cells and adipose-derived stromal cells (ADSCs) are used in cell-based therapy. Data relating to the stem cell therapy and processes associated with ADSC has developed remarkably in the past 10 years. As medical options, both the stromal vascular and ADSC suggests good opportunity as marvelous cell-based therapeutics. The some biological features are the main factors that impact the regenerative activity of ADSCs, including the modulation of the cellular immune system properties and secretion of bioactive proteins such as cytokines, chemokines and growth factors, as well as their intrinsic anti-ulcer and anti-inflammatory potential. A variety of diseases have been treated by ADSCs, and it is not surprising that there has been great interest in the possibility that ADSCs might be used as therapeutic strategy to improve a wider range of diseases. This is especially important when it is remembered that routine therapeutic methods are not completely effective in treat of diseases. Here, it was discuss about applications of ADSC to colitis, liver failure, diabetes mellitus, multiple sclerosis, orthopaedic disorders, hair loss, fertility problems, and salivary gland damage.

中文翻译:

再生医学中脂肪来源的基质细胞的综述。

合适的细胞来源用于再生医学的应用是主要问题。各种干细胞已被用于组织工程和再生医学。例如,几种基质细胞已被用作再生医学的治疗选择。例如,人类骨髓来源的基质细胞和脂肪来源的基质细胞(ADSC)用于基于细胞的治疗。在过去的十年中,与干细胞疗法和与ADSC相关的过程有关的数据得到了显着发展。作为医学选择,基质血管和ADSC都有望成为基于细胞的奇妙疗法。一些生物学特征是影响ADSC再生活性的主要因素,包括细胞免疫系统特性的调节和生物活性蛋白(例如细胞因子,趋化因子和生长因子)的分泌,以及它们固有的抗溃疡和抗炎潜力。ADSC已经治疗了多种疾病,因此人们对ADSC可能被用作改善广泛疾病的治疗策略的兴趣就不足为奇了。当记住常规治疗方法不能完全有效地治疗疾病时,这一点尤其重要。在这里,讨论了ADSC在结肠炎,肝衰竭,糖尿病,多发性硬化,骨科疾病,脱发,生育力问题和唾液腺损伤中的应用。以及它们固有的抗溃疡和抗炎潜力。ADSC已经治疗了多种疾病,因此人们对ADSC可能被用作改善广泛疾病的治疗策略的兴趣就不足为奇了。当记住常规治疗方法不能完全有效地治疗疾病时,这一点尤其重要。在这里,讨论了ADSC在结肠炎,肝衰竭,糖尿病,多发性硬化,骨科疾病,脱发,生育力问题和唾液腺损伤中的应用。以及它们固有的抗溃疡和抗炎潜力。ADSC已经治疗了多种疾病,因此人们对ADSC可能被用作改善广泛疾病的治疗策略的兴趣就不足为奇了。当记住常规治疗方法不能完全有效地治疗疾病时,这一点尤其重要。在这里,讨论了ADSC在结肠炎,肝衰竭,糖尿病,多发性硬化,骨科疾病,脱发,生育力问题和唾液腺损伤中的应用。毫不奇怪,人们对将ADSC用作改善广泛疾病的治疗策略的兴趣引起了极大的兴趣。当记住常规治疗方法不能完全有效地治疗疾病时,这一点尤其重要。在这里,讨论了ADSC在结肠炎,肝衰竭,糖尿病,多发性硬化,骨科疾病,脱发,生育力问题和唾液腺损伤中的应用。毫不奇怪,人们对将ADSC用作改善广泛疾病的治疗策略的兴趣引起了极大的兴趣。当记住常规治疗方法不能完全有效地治疗疾病时,这一点尤其重要。在这里,讨论了ADSC在结肠炎,肝衰竭,糖尿病,多发性硬化,骨科疾病,脱发,生育力问题和唾液腺损伤中的应用。
更新日期:2020-08-21
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