Genome editing is unraveling its benefits in wide areas of scientific development and understanding. The advances of genome editing from ZFNs and TALLENs to CRISPRs defines it wide applicability. Reproduction is the fundamental process by which all organisms maintain their generations. CRISPR/Cas9, a new versatile genome editing tool is recently tamed to correct several disease causing genetic mutations spreading its arms to improve reproductive health. It not only edit harmful genetic mutations but is also applied to control the spread of parasitic diseases like malaria by introducing selfish genetic elements, propagated through generations and population via reproduction. These applications made us to review the recent developments of CRISPRs use in reproductive biology.

中文翻译：

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CRISPR/Cas9 在生殖生物学中的应用。

基因组编辑正在揭示其在科学发展和理解的广泛领域中的优势。从 ZFN 和 TALLEN 到 CRISPR 的基因组编辑的进步定义了它的广泛适用性。繁殖是所有生物维持其世代的基本过程。CRISPR/Cas9 是一种新的多功能基因组编辑工具，最近被驯服以纠正几种导致基因突变的疾病，从而改善生殖健康。它不仅可以编辑有害的基因突变，还可以通过引入自私的基因元素，通过繁殖在世代和人口中传播来控制疟疾等寄生虫病的传播。这些应用使我们回顾了 CRISPR 在生殖生物学中使用的最新进展。