Methicillin-resistant Staphylococcus aureus (MRSA) has been one of the most important antibiotic-resistant pathogen in many parts of the world over the past decades. This cross-sectional study was conducted to investigate MRSA isolated between July 2013 and July 2014 in Karaj, Iran. All tested isolates were collected in teaching hospitals from personnel, patients, and surfaces and each MRSA was analyzed by SCCmec and spa typing. Antibiotic susceptibility testing was accomplished by disk diffusion method. Out of 49 MRSA isolates from the Karaj's teaching hospitals, 82%, 10%, and 6% of the isolates were SCCmec types III, II, and I, respectively. The main spa type in this study was spa t030 with frequency as high as 75.5% from intensive care unit (ICU) of the hospitals and high rate of resistance to rifampicin (53%) was found in MRSA isolates. In conclusion, high frequency of spa t030 with SCCmec type III and MRSA phenotype illustrated circulating of one of the antibiotic-resistant strains in ICU of Karaj's teaching hospitals and emphasizes the need for ongoing molecular surveillance, antibiotic susceptibility monitoring, and infection control.

中文翻译：

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在伊朗卡拉伊的教学医院中，高耐甲氧西林金黄色葡萄球菌（MRSA），SCCmec III型和spa型t030。

耐甲氧西林金黄色葡萄球菌（MRSA）在过去几十年中一直是世界上许多地区最重要的抗药性病原体之一。这项横断面研究旨在调查2013年7月至2014年7月在伊朗卡拉伊分离的MRSA。在教学医院中从人员，患者和表面收集了所有测试的分离株，并通过SCCmec和spa分型对每种MRSA进行了分析。通过纸片扩散法完成抗生素敏感性试验。来自Karaj的教学医院的49种MRSA分离株中，分别有82％，10％和6％的SCCmec类型为III，II和I。在这项研究中，主要的水疗中心类型是水疗中心t030，其频率从医院的重症监护病房（ICU）高达75.5％，并且在MRSA分离物中发现对利福平的耐药率较高（53％）。