The omentum is a visceral adipose tissue with unique immune functions. Although it is primarily an adipose tissue, the omentum also contains lymphoid aggregates, called milky spots (MSs), that contribute to peritoneal immunity by collecting antigens, particulates, and pathogens from the peritoneal cavity and, depending on the stimuli, promoting a variety of immune responses, including inflammation, tolerance, or even fibrosis. Reciprocal interactions between cells in the MS and adipocytes regulate their immune and metabolic functions. Importantly, the omentum collects metastasizing tumor cells and supports tumor growth by immunological and metabolic mechanisms. Here we summarize our current knowledge about the development, organization, and function of the omentum in peritoneal immunity.

中文翻译：

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大网膜的免疫功能。

大网膜是内脏脂肪组织，具有独特的免疫功能。虽然大网膜主要是脂肪组织，但它也含有淋巴聚集体，称为乳斑 (MS)，它通过从腹膜腔收集抗原、颗粒和病原体来促进腹膜免疫，并根据刺激促进多种免疫反应。免疫反应，包括炎症、耐受性，甚至纤维化。MS 中的细胞和脂肪细胞之间的相互作用调节它们的免疫和代谢功能。重要的是，大网膜收集转移的肿瘤细胞并通过免疫和代谢机制支持肿瘤生长。在这里，我们总结了目前关于腹膜免疫中大网膜的发育、组织和功能的知识。