Nanotechnology is expected to contribute to the protection of the environment, but many uncertainties exist regarding the environmental and human implications of manufactured nanomaterials (MNMs). Contradictory results have been reported for their ecotoxicity to aquatic organisms, which constitute one of the most important pathways for their entrance and transfer throughout the food web. The present review is focused on the international strategies that are laying the foundations of the ecotoxicological assessment of MNMs. Specific advice is provided on the preparation of MNM dispersions in the culture media of the organisms, which is considered a key factor to overcome the limitations in the standardization of the test methodologies.

中文翻译：

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纳米技术的主要挑战：生态毒性测试的标准化。

纳米技术有望对环境保护做出贡献，但是人造纳米材料（MNM）的环境和人类影响存在许多不确定性。据报导，它们对水生生物具有生态毒性，这是其进入并在整个食物网中传播的最重要途径之一。目前的审查侧重于国际战略，这些战略奠定了多边市场机制的生态毒理学评估的基础。提供了有关在微生物培养基中制备MNM分散体的具体建议，这被认为是克服测试方法标准化限制的关键因素。