Complex communities of microorganisms, termed commensal microbiota, inhabit mucosal surfaces and profoundly influence host physiology as well as occurrence of allergic diseases. Perturbing factors such as the mode of delivery, dietary fibers and antibiotics can influence allergic diseases by altering commensal microbiota in affected tissues as well as in intestine. Here, we review current findings on the relationship between commensal microbiota and allergic diseases, and discuss the underlying mechanisms that contribute to the regulation of allergic responses by commensal microbiota.

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超越卫生：共生微生物群和过敏性疾病

复杂的微生物群落，称为共生微生物群，栖息在粘膜表面，深刻影响宿主生理和过敏性疾病的发生。诸如给药方式、膳食纤维和抗生素等干扰因素可以通过改变受影响组织和肠道中的共生微生物群来影响过敏性疾病。在这里，我们回顾了目前关于共生微生物群与过敏性疾病之间关系的发现，并讨论了共生微生物群调节过敏反应的潜在机制。